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# CITATION file created with {cffr} R package
# See also: https://docs.ropensci.org/cffr/
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cff-version: 1.2.0
message: 'To cite package "tepr" in publications use:'
type: software
license: GPL-3.0-only
title: 'tepr: Transcription Elongation Profiling'
version: 1.1.15
doi: 10.32614/CRAN.package.tepr
abstract: The general principle relies on calculating the cumulative signal of nascent
  RNA sequencing over the gene body of any given gene or transcription unit. 'tepr'
  can identify transcription attenuation sites by comparing profile to a null model
  which assumes uniform read density over the entirety of the transcription unit.
  It can also identify increased or diminished transcription attenuation by comparing
  two conditions. Besides rigorous statistical testing and high sensitivity, a major
  feature of 'tepr' is its ability to provide the elongation pattern of each individual
  gene, including the position of the main attenuation point when such a phenomenon
  occurs. Using 'tepr', users can visualize and refine genome-wide aggregated analyses
  of elongation patterns to robustly identify effects specific to subsets of genes.
  These metrics are suitable for internal comparisons (between genes in each condition)
  and for studying elongation of the same gene in different conditions or comparing
  it to a perfect theoretical uniform elongation.
authors:
- family-names: Descostes
  given-names: Nicolas
  email: nicolas.descostes@gmail.com
- family-names: Billon
  given-names: Victor
  email: victor.billon@etu.univ-cotedazur.fr
- family-names: Cristofari
  given-names: Gael
  email: gael.cristofari@cnrs.fr
repository: https://descostesn.r-universe.dev
commit: 343005602d564bc29cca693f5199802a1e4c2c29
date-released: '2026-03-05'
contact:
- family-names: Descostes
  given-names: Nicolas
  email: nicolas.descostes@gmail.com